Interval Timing Deficits and Abnormal Cognitive Development

Interval Timing Deficits and Abnormal Cognitive Development

mance even for relatively small sample sizes (Szelag et al., 2004). Thus, in spite of the lack of universality of interval timing deficits, the increased incidence rate needs to be explained. Moreover, it has been suggested that ADHD and ASD share some susceptibility genes (Castellanos and Tannock, 2002), which makes it likely that some dysfunctions are shared between them or their subtypes. We...

Journal of Abnormal Psychology Emotion Deficits in Schizophrenia: Timing Matters

A firing rate model of Parkinsonian deficits in interval timing.

To account for deficits in interval timing observed in Parkinson's Disease (PD) patients, we develop a model based on the accumulating firing rate of a neural population with recurrent excitation. This model naturally produces the curvilinear accumulation of neural activity introduced to timing psychophysics by Miall (Models of Neural Timing, Elsevier Science, 1996), and implicated in Parkinson...

Interval Timing Deficits Assessed by Time Reproduction Dual Tasks as Cognitive Endophenotypes for Attention-Deficit/Hyperactivity Disorder

The literature has suggested timing processing as a potential endophenotype for attention deficit/hyperactivity disorder (ADHD); however, whether the subjective internal clock speed presented by verbal estimation and limited attention capacity presented by time reproduction could be endophenotypes for ADHD is still unknown. We assessed 223 youths with DSM-IV ADHD (age range: 10-17 years), 105 u...

Schizophrenia: Cognitive Deficits and Perceptual Deficits

Schizophrenia is a complex and severe mental disorder that affects about 1% of the population, clinically characterized by positive, negative, and disorganized symptoms. It is widely accepted that a combination of genetic and environmental factors lead to the onset of schizophrenia. The past two decades have witnessed the increasingly important role of cognitive deficits in schizophrenia, such ...